Tuesday, March 31, 2009

Fibromyalgia remission with Malarone

I have been treating a 46 year old woman with chronic Lyme syndrome for about 18 months. She resides in Montgomery County Maryland and her favorite hobby is(was) gardening. Her presenting complaints were muscle pain, muscle weakness, fatigue, joint pain, neck pain, headaches- with an exacerbation of pre-existing migraines, night sweats, brain fog with forgetfulness- word recall difficulties- short term memory loss- slow cognitive processing and severe depression. She in fact had no idea that she might be suffering with chronic Lyme disease when I suggested the diagnosis. She had been a regular patient for several years treated only for migraine headaches. She had not shared her other symptoms with me because she was worried that I would think she was a hypochondriac. The muscle pain it turns out, was a prominent symptom. She had incapacitating pains in her muscles, especially around her neck and upper back area. Her muscles were knotted and stringy and exquisitely tender. She saw a pain management specialist who diagnosed "fibromyalgia," and treated her with trigger point injections as well as a mix of pain meds. This occurred during the 6 months prior to the Lyme diagnosis. Looking back, it is now clear that she had suffered with fibromyalgia for 20 years. She did not share her symptoms with others in her life. She blamed herself. Somehow, she believed her symptoms represented a personal failing- as she struggled to keep up with other well functioning people around her. Only by sheer will and determination was she able to create the illusion that she was well, when in fact she was getting sicker and sicker.

Finally, almost inadvertently, she shared her story with me.

Her exam had classic Lyme neurological abnormalities. Her labs were fairly unremarkable. Her IgeneX WB for Lyme showed only a positive IgM 31 band with several other IND bands. She wanted a positive test to be convinced she really had Lyme disease. I explained that the 31 band was highly specific. It took some coaxing, but she agreed to start treatment for Lyme. She took Amoxil and Biaxin for about one year. She was nervous about changing medications so we kept to this one regimen. Most of her symptoms improved. Overall, she was 60% better. Persisting symptoms included sweats- which thought were due to menopause AND there had been no change in the fibromyalgia piece of her syndrome. I convinced her to try Mepron, believing that she had sero-negative Babesia. Her insurance turned down Mepron so I substituted Malarone, perhaps fortuitously. Follow up labs continued to be seronegative for Lyme disease by IgeneX standards and Babesia. I also ordered a blood wet mount performed at Clongen. Extracellular motile organisms were present.

After 3 months on Malarone she noted that the muscle pain was almost completely gone. After five months on Malarone all signs and symptoms of fibromyalgia were 100% gone. Her knotty,lumpy muscles were replaced with smooth, normal tissues. This is one very happy patient! Her "menopausal" sweats were also gone.

This is conjecture: She never had Babesia. The motile parasites seen in blood wet mounts may have been responsible for her muscle disorder. We known that these parasites do not live in blood or blood cells- they are extracellular. This means they primarily reside in other tissues. Their numbers must be so numerous that they egress into the blood. A likely place for parasites to live is muscle tissue. One must wonder: could fibromyalgia be caused by muscle parasites, at least in some patients?

This case shows remission of longstanding fibromyalgia with Malarone- used in conjucntion with Biaxin and Amoxicillin.

8 comments:

Starlings Preschool said...

Wow! do you think this parasitical organism is the same thing that the Fry Lab has found in Lyme pt's blood? It is similar to toxoplasmosis.

This woman had Lyme, but you think no babesia? Why not babesia in addition to this organism?

cehansen said...

how much malarone Lyme MD? I fit this clinical picture and had no response to Mepron.

Ilona said...

Malarone worked wonders on me. The day I started Malarone and Plaquenil was the day the myoclonus and fasciculations were halved. Just fyi...

JOHNSON KATE said...

As a sign of gratitude for how my son was saved from fibromyalgia , i decided to reach out to those still suffering from this.
My son suffered fibromyalgia in the year 2013 and it was really tough and heartbreaking for me because he was my all and the symptoms were terrible, he always complain of joint stiffness, and he always have difficulty falling asleep . we tried various therapies prescribed by our neurologist but none could cure him. I searched for a cure and i saw a testimony by someone who was cured and so many other with similar body problem, and he left the contact of the doctor who had the cure to fibromyalgia . I never imagined fibromyalgia has a natural cure not until i contacted him and he assured me my son will be fine. I got the herbal medication he recommended and my son used it and in one months time he was fully okay even up till this moment he is so full of life. fibromyalgia has a cure and it is a herbal cure contact the doctor for more info on drwilliams098765@gmail.com on how to get the medication. Thanks for reading my story

SOPHIE LEWIS said...

I am Sophie from Canada, I once suffered from a terrible and Chronic fibromhyalgia,since i was bone , the doctor told me there was no permanent cure i was given medications to slow down its progress, i constantly felt my health was deteriorating as i constantly had Painful menstrual periods,this ailment was really terrible especially when am going out with my friends, i have this constant disorder for about 31 years, this was really a terrible ailment ,on thin one day that i was going through the internet,and i came across a post of Mrs jessica on how his daughter was been cured from fibromhyalgia through the help of Dr Williams herbal product, I contacted this herbal doctor via his email and explain everything to him and make purchase of his product,few days later he sent me the herbal medicine through courier service, when i received the herbal medicine, i used it for 1 months and two weeks as prescribed by dr williams and i was totally cured within those week of usage,on thin now i have not experience any sign or characteristics again . for more information you can email him on drwilliams098675@gmail.com for help

Sadhna Vats Vats said...

CURE TO FIBROMYALGIA WITHOUT ANY SIDE EFFECT: My husband was diagnosed with fibromyalgia . My husbad fibromyalgia was something i don't understand he cry so bad that he was usually in bed for about 8 hours and soreness killers (even prescription strength) don't stop the weakness of the joint, even if he take triple the dosage. my husband symptoms was really so terrible,that we have to make hospital our home, and all the doctors would do is monitor it, prescribe him countless of control pills and pain medication with no positive result. until recently I contacted a Doctor who put an end to this problem. If you are having same problem with fibromyalgia contact Dr. William for advice and possible solution without any side effect (drwilliams098675@gmail.com

Unknown said...

MY NAME IS BILLIE LORA FROM USA.
With Dr Williams herb i was completely free from fibromyagia.You are an amazing doctor.Matching diagnosises aside, I just want to be your friend. Lol You inspire me on a feminist level. On an intelligence level. you are a good man doing so much for mankind, level.Thank you for being you.For keeping a lot of us . For reminding us that we aren’t a fucking statistic or a status, we are still PEOPLE. With brains and personalities and jobs and lives. I’ve been diagnosed for so many years now with fibromyalgia, and the roller coaster of emotions is all too real.I’m sure I speak for everyone here when I say thank you. From the deepest part of my soul. THANK YOU.You give us all an indescribable level of comfort and absurdness in sharing our diagnoses and, almost a green light to continue to celebrate our lives,for you always been there.For every jerk who throws you hate, there are hundreds of us thanking the universe for you.for more information about Dr Williams product to fibromyalgia you can email him on drwillliams098675@gmail.com

Helen Snoddy Beaver said...

9 YEARS FIBROMYALGIA CURED WITH HERBS: I am so happy sharing my mom's story of Fibromyalgia that almost ruined family of its happiness. It is known now that there is permanent cure to Fibromyalgia, to those still in doubt of this, my mom is a living Testimony. For 9yrs, my mom suffered from Fibromyalgia, many investigations have did took place to achieve a diagnosis, it came from nowhere. She is one of those millions of people around the world who suffered Fibromyalgia until God healed her completely with HIELAN Herbal Medications for fibro by Dr. Rodwen Thompson. the symptoms she was experiencing ranges from general tiredness lethargy to being properly depressed, isolated, feeling hopeless and miserable maybe because of the constant back pain that seem to get worse and worse on daily basis, pains down both arms, hips, legs, across her shoulders, right hand side of her back, left hand side of her neck, sometimes head as she said the pains were excruciating. She can never sleep at night when bad tingling all over her body cramps and temperature fluctuations, but do sleep a little at noon. Hospital became our second home until she finally received a definite diagnosed. I cry every day because I feel I was losing my mom. We search and search for help everywhere possible but none was forth coming. To cut the long story short, HIELAN brought us breakthrough. The Herbs proved very effective just after 3 months of use; today she is totally free from Fibro with no side effects. To know more about this product, visit: curetofibromyalgia.blogspot.com or you can write him directly via: dr.rodwenthompson@gmail.com. After she was cured, I realized that Our search for light begins when we get fed up with gross darkness.