An 18 year old female with an 11 year history of complex multisystem Lyme disease recently had an upper endoscopy for the evaluation of persistent unexplained gastrointestinal symptoms.
Biopsy samples taken from the stomach and duodenum were sent to Clongen labs for PCR analysis. The samples were tested for Mycoplasma fermentans, Borrelia burdorferi, Babesia microti and Bartonella henselae. These specific tests were chosen by Dr. Ray Jones. This patient is new to me and has recently requested that I contribute to her case.
THE STOMACH TISSUE PCR TESTED POSITIVE FOR BORRELIA BURDORFERI!
Looking for Lyme by PCR has been difficult because it has not been clear which tissue should be biopsied. Here is a case demonstrating the persistence of the Lyme bacteria in gastric mucosal tissues after 5 years of continuous antibiotic therapy.
This begs the question: Should gastric Lyme be treated differently. Perhaps the acid environment enhances survival of the organism. Drawing from the H. pylori experience, it may be helpful to treat with high dose proton pump inhibitor therapy in addition to combination antibiotics.
Here we are sailing on uncharted waters.