I am dragging my butt around today because I started reading Weintraub's book with above title last night. I couldn't put it down and finished reading at 2 AM. Great read! She spent 6 years on the book and provides invaluable insights as to how we got to where we are now. It reads like a novel: the politics, the personalities, the egos, the intellectual fraud, the vitriol, the personalization and degradation of what should have been dispassionate discussions amongst caring professionals into an all out street brawl with all the trimmings, the distortions, the lies, the backstabbing, the selective use of science to accommodate forgone conclusions, the "high tech lynching" of professionals by others with more "power" and testosterone; its all there in plain view. The patients who are left out in the cold are also clearly depicted. She talks about "Lymeland," a secret place where "Lymies" and their docs go, underground and in the shadows.
She said she had trouble ending the book. I hope that is because the final chapter has not yet been written. She talks about the 3 NIH studies relating to chronic Lyme. She exposes the deceit and treachery of those involved. The IDSA holds fast: there is no chronic Lyme. The Klempner study (which is open to much criticism) showed no benefits with prolonged antibiotics. But wait a minute. The Krupp study showed marked improvement in the target symptom, fatigue. The Fallon study for neuroborreliosis showed dramatic improvement which was transient and returned when intensive antibiotics were resumed. I must of failed math. Two of three high level studies demonstrated that chronic Lyme responds to long term antibiotics. The IDSA only looked at one study and ignores the other two. They must be better at math than me ( I went to a State University, not an Ivy League one) . She presents a wealth of data from animal models, but this doesn't count either. Maybe only in horseshoes and hand grenades? My only curiosity about the book is why she decided to completely omit the whole L-form issue. She certainly mentions more controversial issues including Mycoplasma fermentans.
Double kudos to Pamela Weintraub!