Thursday, June 2, 2016

The Lyme brain and nootropics


Cognitive impairment is one of the most disabling symptoms seen in patients with Lyme disease.  The symptoms can be quite subjective. The symptoms can be very disconcerting and at times disabling. The complaint is almost universally overlooked by general physicians and neurologist. After all, there is no evidence of dementia.  Many patients will pass neurocognitive testing, rarely offered and quite expensive. SPECT scans, infrequently performed, may or may not be abnormal and when abnormal brushed off as nonspecific. But as a patient recently shared with me, before Lyme she performed great at a high level job requiring timely completion of complex intellectual tasks; she can still get the job done but it takes 3 times as long. On this basis it is no longer financially viable for her to continue the consulting work and she is applying for disability. Doctors tell their patients: its normal to be a little slower after 50, it is natural for math skills to slip a bit.  Increased difficulty with word retrieval is par for the course with middle age.  Maybe to some extent this is true, but Lyme patients experience something qualitatively – and quantitatively different.  Mainstream medicine with its black and white world view is deaf and blind to the complaints of Lyme sufferers who may: get lost, confused, space out and put their cell phones in the fridge. If it is not Alzheimer’s disease, frontotemporal dementia, Lewy body disease, a brain tumor, a subdural hematoma, hydrocephalus, a prion disease or a few other conditions patient are told there is nothing to worry about. We know differently.  Of course the same Lyme patients complaining of brain fog also complain of fatigue. Frequently the two are intimately connected and it is hard to separate cognitive issues related to fatigue from those that exist independently. The question then is: what, if anything can be done? 
Clearly if we are dealing with germs in the brain we need to use antimicrobial agents which are powerful, able to penetrate into the brain and able to target the specific organisms of concern.  Typically, the focus is on spirochetes, pleomorphic variants, blood parasites, bacteria in blood vessels, biofilms and perhaps other organisms, like worms.

What else?  How do we make the brain work better?

Drugs that make the brain work better are called nootropics. The best known are stimulants.  Drugs like Provigil help with wakefulness. Clearly treating fatigue may help. Drugs like Ritalin, Adderall help with focus, attention and task performance. These drugs impact the neurotransmitter dopamine and are particularly active in the frontal lobe, executive function area of the brain.

Drugs like Namenda, commonly used in Alzheimer’s disease, negate excessive activity of the neurotransmitter glutamic acid caused by brain inflammation and related neurotoxins. Patients on this drug frequently find they are able to think more clearly.
Cholinergic drugs promote the activity of acetylcholine, a neurotransmitter involved with memory and other cognitive functions.  Rather than a prescription drug, I have found the supplement Procera (or similar) to positively impact cognition.

Do bile acid binders, cholestyramine and Welchol help?  In some patients the answer seems to be yes. I am not sure why.  Toxins?  I don’t think so. The prototypic neurotoxin, QUIN does not cross the blood brain barrier well, hence the use of drugs like Namenda. However, bile acids and cholesterol, both of which are lowered with bile acid sequestrants have signaling effects in the brain.

Glutathione may help, but only IV.  It may reduce the burden of free radicles, reactive species causing oxidative stress, negatively impacting function of neurons. In addition, mitochondrial dysfunction is directly connected to oxidative stress. Alleviated the latter promotes function of the former. Mitochondria in brain cells are essential for the production of energy.
Ketone bodies?  Some patients experience incredible improvements on an Atkins like diet. A ketogenic diet changes the brains fuel from primarily to glucose to primarily ketone bodies. This may result in neuroprotection, decreased brain inflammation, decreased oxidative stress and better mitochondria function.  Perhaps ketone supplements help as well.

Hyperbaric oxygen therapy.  For practical reasons most patients only have access to home units with offer a low pressure. A new unit can be purchased for as little as 5500 dollars. Patients who do the best spend 2 hours or more per day in the chamber. The treatment reduces oxidative stress, promotes glutathione and has been specifically shown to improve neuroplasticity with reversal of abnormal SPECT scan patterns.

Food for thought


( Nothing here should be construed as specific medical advice)

31 comments:

Jill Grosh said...

COMPLETE CURE TO LYMES: My brother was infected by a lyme disease for 10 years, it started with Rash, Fever, Fatigue and Head ache, It then later worsened (Chronic). I have tried many treatment suggested by the Guru which include Antibiotics, and more other medicine prescribed but all to no avail. Lately I was directed to a Doctor called William, who provided solution to the problem. Do not be discourage, it is a permanent treatment/cure to Lyme Disease, Contact him with this email for more info: (drwilly37@ gmail. com)

Ryan Smith said...
This comment has been removed by the author.
Ryan Smith said...
This comment has been removed by the author.
bhavinder rao said...

Sometimes i tries the Inteligen Nootropics brain supplement it works good

Houston Huffard said...

Admin please help me pass this on.
I have lived a very terrified life the past 12 years due to the steady distraction caused by tinnitus. I hear a steady, offensive and unending buzzing sound on my left ear, which made me deaf. I worked in a factory for 28 years and i was really much exposed to loud noise, since i retired 15 years ago i have been faced with this, infact it made me deaf. I was fortunate enough to get a medicine from Dr. Joseph that put a final stop to the sound and it has never returned since then. Most doctors might tell you there is no cure but as a survivor of this i will tell you it is curable. To get the medicine for yourself just reach him personally on josephalberteo@gmail.com also for advise and information too.

stephen gutierrez said...

Dr.William product is a real cure to Tinnitus, I am 38 years old, I suffered from permanent tinnitus for about 10 years, mostly in my right ear... which means I've got this constant ringing in my ears, which has also made me somewhat deaf. It's like this Whee! noise in my head all the time. My T was more steady, this is due to prolonged exposure to the loud volume of concerts. Looking after your ears is unfortunately something you don't think about until there's a problem. I wish I'd thought about it earlier. There were days when I didn't know whether I would survive, I was so tormented by this symptoms. When I lay down to sleep it bothers me the most, As I lay my head on the pillow, it cancels out all the other noise but the Tinnitus. The GoodNews is that after using William Herbal medicine, Tinnitus is gone, try it also it may work for you. There are real cure and do not be discouraged. Hang in there... Better days will come (email: drwilliams098765@gmail.com).

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ANA MARIA said...

Dr.William product is a real cure to Tinnitus, I am 38 years old, I suffered from permanent tinnitus for about 4 years, mostly in my right ear... which means I've got this constant ringing in my ears, which has also made me somewhat deaf. It's like this Whee! noise in my head all the time. My T was more steady, this is due to prolonged exposure to the loud volume of concerts. Looking after your ears is unfortunately something you don't think about until there's a problem. I wish I'd thought about it earlier. There were days when I didn't know whether I would survive, I was so tormented by this symptoms. When I lay down to sleep it bothers me the most, As I lay my head on the pillow, it cancels out all the other ear. The GoodNews is that after using William Herbal medicine, Tinnitus is gone, try it also it going to work for you. There are real cure and do not be discouraged. Hang in there... Better days will come (email him on: drwilliams098765@gmail.com)

Karen Dish said...

How can I ever stop thanking Dr William for the great thing he have done for me, i got an accident when I was 27 years old from that day on i started experience ringing ear problem(tinnitus) i have taken all the western drugs prescribe by various doctor but to no avail . my tinnitus was very loud in the afternoon and I sleep less at night because of this problem i stop my work, few days later i was going through the Internet and I saw a post of a woman testifying about Dr William herbal remedies on how she was being cure for over her 30 years suffering from tinnitus the story Really motivated me that I have to speak with my husband about it, and he said i should give him a try, i contacted Dr William and explain all i have be facing in my life. He assured me that everything is going to be fine if only I can get his herbal portion, i said yes and I requested for it, few days later the herb was sent to me in Kuwait,i started using it as instructed by Dr William for me to take it for 21 Days which I did, can you imagine after talking Dr William herbal medicine for just two weeks i started experience results, it was like a miracle,and now i am permanently cure from this terrible tinnitus, i promise that am going to publish his herb on thing my last breath for the great deed he have done for me. For those with similar ear problem should please contact him on his email address drwilliams098765@gmail his a good man and am proud of him.

Akbar Amir said...

I have beeen following this blog for a while now and today i decided to share my tinnitus story to encourage someone out there. I suffered from terrible tinnitus for 8 years after a constant exposure to loud noise. These noise sounded like a car horn in my right ear and grew worse at night when everywhere was calm and quiet, i lacked sleep and this ruined my psychological life. I had no idea the sound was damaging my hearing until it was too late and i had partial deafness, i had a constant ringing in my ear which always makes me feel like taking my own life. I tried so many drugs even B-vitamin supplements, especially B-5, visited so many audiologist, neuromonics and all was to no avail. I have not seen my ex for a long while and when we bumped into each other she knew i was not okay and i had to tell her all i was facing. She felt so sad but told me there is a cure which let me in amazement. That was when she told me about Dr. Joseph herbal medicine which gives a permanent relief to tinnitus symptoms and cures it. Lord know i needed help so i got the medicine and used it, that was when i met a breakthrough, i am perfectly okay now and i sleep calm without any stress and i hear clearly now. You too can get cured just contact him on (josephalberteo @ gmail. com) for advise and how to get the medicine. Thanks

PAUL said...

DR WILLIAMS HERBAL CURE TO TINNITUS

Appreciation is the key to doing more that is why I have took some time out to thank some one who cured me of my 4 years tinnitus problem. It became a major problem to me as it was affecting my marital life and I was no longer comfortable so I decided to look for a solution and I came across a post of Dr williams and how he has been helping people of the same problem with his herbal remedies I contacted him and told him all I have been facing in my life. He told me how to get his product and how to take it after every thing I find out that all was now okay with me and that my tinnitus problem was gone that is why I have come out today to say thank you to him and for any tinnitus problem either from man or woman. Contact him on drwilliams098765@gmail.com his a man that take good care of his children

faith harry said...

DR GEORGE HERBAL CURE TO EPILEPSY
I was always praying to have a testimony when ever i saw people sharing their own testimonies which really took me years but today i am the happiest father on earth.
My son suffered EPILEPSY, for 20years after taken different kind of western medication without been cured.
All these years my son was like a death person but today he is been cured.and you do not know how i feel having my son back to life because it was not really easy for me having just two children and one been abnormal.
I took time to search internet which i found a lot of people thanking Dr. George concerning the same problem and i discussed it with my wife and she said we should give a try so we order his product which my son took for some months and he is very much okay now.
I will advise you stop wasting time on all these western medicine because they only work for some
days and the problem bounce back again.
Contact Dr. at drgeorge2580@gmail.com for advice and for his product and be the next to give testimony

PAUL said...

DR WILLIAMS HERBAL CURE TO TINNITUS

Appreciation is the key to doing more that is why I have took some time out to thank some one who cured me of my 4 years tinnitus problem. It became a major problem to me as it was affecting my marital life and I was no longer comfortable so I decided to look for a solution and I came across a post of Dr williams and how he has been helping people of the same problem with his herbal remedies I contacted him and told him all I have been facing in my life. He told me how to get his product and how to take it after every thing I find out that all was now okay with me and that my tinnitus problem was gone that is why I have come out today to say thank you to him and for any tinnitus problem either from man or woman. Contact him on drwilliams098765@gmail.com his a man that take good care of his children

Jessical Alba said...

COMPLETE CURE TO TINNITUS: I had tinnitus in both ears for fifteen years with a high pitched two tone sound, the noises are constant and have learned to ignore the ringing. Later, another sound was added, a deep tone that has a sporadic rhythm, that mimics human speech. It varies from soft and muted, to painfully clear, and loud. Have try sound machines, ear plugs, my hearing aid, and medication all to no avail rather I have a difficult time sleeping. Lately I was directed to a Doctor called William on internet who provided solution to the problem. Do not be discourage, dr williams product is a permanent cure to Tinnitus. Contact him with this email (drwilliams098765@gmail.com)

PAUL said...

DR WILLIAMS HERBAL CURE TO TINNITUS

Appreciation is the key to doing more that is why I have took some time out to thank some one who cured me of my 4 years tinnitus problem. It became a major problem to me as it was affecting my life and I was no longer comfortable so I decided to look for a solution and I came across a post of Dr williams and how he has been helping people of the same problem with his herbal remedies I contacted him and told him all I have been facing in my life. He told me how to get his product and how to take it after every thing I find out that all was now okay with me and that my tinnitus problem was gone that is why I have come out today to say thank you to him and for any tinnitus problem either from man or woman. Contact him on drwilliams098765@gmail.com his a man that take good care of his children

buay marry said...

thankes to Dr ebhota, who cured me of fallopian tube blockage and fibroid. i married for over eight years wthout a child of my own. because of the problem with my fallopian tubbe and fibroid, until i came in conntact with Dr ebhota's testimony and recommendations online, on how he has cured and healed so many people of the same illment, and i decided to contact him, and he administered his medicatons on me, and i became pregnant in two months. increase you want to reach him for a similar problem, you can reach him on +2347086564868 or email him,drebhota123456@gmail.com

Jessical Alba said...

COMPLETE CURE TO TINNITUS: I had tinnitus in both ears for fifteen years with a high pitched two tone sound, the noises are constant and have learned to ignore the ringing. Later, another sound was added, a deep tone that has a sporadic rhythm, that mimics human speech. It varies from soft and muted, to painfully clear, and loud. Have try sound machines, ear plugs, my hearing aid, and medication all to no avail rather I have a difficult time sleeping. Lately I was directed to a Doctor called William on internet who provided solution to the problem. Do not be discourage, dr williams product is a permanent cure to Tinnitus. Contact him with this email (drwilliams098765@gmail.com)

JOHNSON KATE said...

ALL THANKS TO DR WILLIAMS WITH HIS HERB I WAS CURED FROM A TERRIBLE TINNITUS.
. Is my pleasure to comment on this site and i thank the admin of this site for his/her great work so far. I really don’t know how to thank DR WILLIAMS for helping me get cured for over 20 year of suffering from a terrible tinnitus, my tinnitus started when i was 28 year i thought is going to end one day but even get worse as days went by,i have tried all western drugs prescribed by doctors but to no avail, even at night i screams even more because the sounds become louder because everywhere is quiet. i came across DR WILLIAMS contact through a headline news on internet about how DR WILLIAMS have help so many people to get cured of tinnitus and so many other with similar body problem ,i contacted him and he told me how to get his herb,few day later he sent me the herbal portion which i take every morning for 21 days, and his medicine was able to restore me back to normal and now am very okay without any side effects whatsoever If you have Tinnitus, you can contact him on his email address drwilliams098765@gmail.com for help

Jessical Alba said...

COMPLETE CURE TO TINNITUS: I had tinnitus in both ears for fifteen years with a high pitched two tone sound, the noises are constant and have learned to ignore the ringing. Later, another sound was added, a deep tone that has a sporadic rhythm, that mimics human speech. It varies from soft and muted, to painfully clear, and loud. Have try sound machines, ear plugs, my hearing aid, and medication all to no avail rather I have a difficult time sleeping. Lately I was directed to a Doctor called William on internet who provided solution to the problem. Do not be discourage, dr williams product is a permanent cure to Tinnitus. Contact him with this email (drwilliams098765@gmail.com)

karen dish said...

ALL THANKS TO DR WILLIAMS WITH HIS HERBAL PORTION I WAS COMPLETELY CURED FROM A TERRIBLE TINNITUS.
How can I ever stop thanking Dr William for the great deed he have done for me, i got an accident when I was 27 years old, from that day on i started experience ringing ear (tinnitus) i have taken all the western drugs prescribe by various doctor but to no avail . my tinnitus was very loud in the afternoon and I sleep less at night because of this problem i stop my work, few days later i was going through the Internet and I saw a post of so many people testifying about Dr William herbal remedies on how they was being cure for over many years suffering from tinnitus the story Really motivated me that I have to speak with my husband about it, and he said i should give him a try, i contacted Dr William and explain all i have be facing in my life. He assured me that everything is going to be fine if only I can get his herbal portion, i said yes and I requested for it, few days later the herb was sent to me in Kuwait,i started using it as instructed by Dr William for me to take it for 21 Days which I did, can you imagine after talking Dr William herbal medicine for just two weeks i started experience results, it was like a miracle,and now i am permanently cure from this terrible tinnitus, i promise that am going to publish his herb on thing my last breath for the great deed he have done for me. For those with similar ear problem should please contact him on his email address drwilliams098765@gmail his a good man and am proud of him.

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mattias lang said...

I am Matthias lang, from Orlando u s a, i was diagnosed with tinnitus for 6 years, i lived in pain with the knowledge that i wasn't going to ever be well again, i contacted so many doctors on this issue,and i have use so many western drugs prescribe by various doctors and all was no avail, because i was determined to get my life back, one day i was researching for this disease on internet and i saw a post about devansh herbal health care who cure different manners of diseases, including tinnitus, I contacted them via email: devanshherbalheathcare@gmail.com and made purchase of the tinnitus herb, i received the herb through USPS within 24 hours, when i received the herb i applied it as prescribed and i was totally cured of tinnitus within few's days of usages,and on thin now i have never experience any ringing in my ears again,few days later i went back to my doctor and he confirmed i was completely cured from this disease, am so happy now, You do not have to suffer more just contact him for his medicine on devanshherbalheathcare@gmail.com.com he will definitely put an end to that hearing problem of yours

JOHNSON KATE said...

ALL THANKS TO DR WILLIAMS WITH HIS HERB I WAS CURED FROM A TERRIBLE TINNITUS.
. Is my pleasure to comment on this site and i thank the admin of this site for his/her great work so far. I really don’t know how to thank DR WILLIAMS for helping me get cured for over 20 year of suffering from a terrible tinnitus, my tinnitus started when i turns 28 we all thought is going to end one day but even get worse as days went by,i have tried all western drugs prescribed by doctors but to no avail i lost total concentration, even at night i screams even more because the sounds become louder because everywhere is quiet. i came across DR WILLIAMS contact through a headline news on internet about how DR WILLIAMS have help so many people to get cured of tinnitus and so many other with similar body problem ,i contacted him and he told me how to get his herb,few day later he sent me the herbal portion which i take every morning for 21 days, and his medicine was able to restore me back to normal and now am very okay without any side effects whatsoever If you have Tinnitus, you can contact him on his email address drwilliams098765@gmail.com for help

Jessical Alba said...

COMPLETE CURE TO TINNITUS: I had tinnitus in both ears for fifteen years with a high pitched two tone sound, the noises are constant and have learned to ignore the ringing. Later, another sound was added, a deep tone that has a sporadic rhythm, that mimics human speech. It varies from soft and muted, to painfully clear, and loud. Have try sound machines, ear plugs, my hearing aid, and medication all to no avail rather I have a difficult time sleeping. Lately I was directed to a Doctor called William on internet who provided solution to the problem. Do not be discourage, dr williams product is a permanent cure to Tinnitus. Contact him with this email (drwilliams098765@gmail.com

marian jack said...

My son recently started having grand Mal seizures at 16 years old. We were prescribed Kepler. We decided NOT to take the medicine and go with a Modified Atkins Diet that entails feeding our son 15 carbs a day with lots of healthy fat. He eats a lot of grass fed beef, free range eggs, organic low crab veggies and is doing fantastic! We could tell a difference in him by the 3rd day. This is not alternative or junk science. Dr. Lewis hill at Johns Hopkins has been championing this diet for years and has been really successful. Doctors are really resistant to this therapy but it works!. Read "Grain Brain" for why it works. He also takes taurine which helped stop the night time teeth grinding, jerking, and unrest in his sleep (also known to stop seizures). And he takes cur cumin as a brain protestant that raises seizures.one day came across Albert post thanking Dr Lewis hill for curing his son seizure problem, and i got the contact of Dr Lewis hill i quickly contacted him then he made me to know that the medication is 100% permanent cure, and that was how i got the medicine which i used for my son, after which i took my son for medical test It worked! Over a year now, my son have not show any symptoms of seizure and I believe my son is cure if you need his help email him on drlewishill247@gmail.com

NITA AMELIA said...

Dr Williams herbal medicine is really a complete and permanent cure to tinnitus with his herbal portion am now also free from the ringing in my ears .

JOHNSON KATE said...

ALL THANKS TO DR WILLIAMS WITH HIS HERB I WAS CURED FROM A TERRIBLE TINNITUS.
. Is my pleasure to comment on this site and i thank the admin of this site for his/her great work so far. I really don’t know how to thank DR WILLIAMS for helping me get cured for over 20 year of suffering from a terrible tinnitus, my tinnitus started when i was 28 year i thought is going to end one day but even get worse as days went by,i have tried all western drugs prescribed by doctors but to no avail i lost total concentration, even at night i screams even more because the sounds become louder because everywhere is quiet. i came across DR WILLIAMS contact through a headline news on internet about how DR WILLIAMS have help so many people to get cured of tinnitus and so many other with similar body problem ,i contacted him and he told me how to get his herb,few day later he sent me the herbal portion which i take every morning for 21 days, and his medicine was able to restore me back to normal and now am very okay without any side effects whatsoever If you have Tinnitus, you can contact him on his email address drwilliams098765@gmail.com for help

SOPHIE LEWIS said...

I am sophie from Canada, I once suffered from a terrible and Chronic tinnitus ,in 2016, the doctor told me it has no permanent cure i was given medications to slow down its progress, i constantly felt my health was deteriorating as i constantly go out of breath,and this noise was really terrible especially when am sleeping, i have this constant ringing in my ears for about 8 months, this was really a terrible noise ,on thin one day that i was going through the internet,and i came across a post of Mrs Kate on how she was been cured from tinnitus through dr Williams herbal product, I contacted this herbal doctor via his email and explain everything to him and make purchase of his product,few days later he sent me the herbal medicine through courier service, when i received the herbal medicine i used it for 3 weeks as prescribed and i was totally cured of tinnitus within those week of usage,on thin now i have not hear anything ringing in my ears.if you need his help you can Contact this herbal doctor via his email drwilliams098765@gmail.com for help

LEONERDO DICAPRIO said...

I have been in the tinnitus community for a while now and I have experience what you are going though with tinnitus , I do know people that have got
tinnitus from having their implants done. Ringing in the ear after an implant can go away on its own, but that is BS of what the mouth and jaw specialist said. I have definitely seen and heard of a connection between tinnitus and teeth and mouth. There is a treatment for ringing ears and if you are
interested you can contact Dr William herbal remedies that what I take that stop the ringing in my ear that was really driving me crazy, don't Lose hope .,I have found a solution for my fellow citizens . If you haven't I would suggest trying Dr William herbal supplement. Again, this is a thing that takes time and usually requires time and patience for it to work WITH no side effects. But I'm not hear to sell you the product, I'm only hear to tell you that it works, but it is a journey and can be difficult. I hope at this point in want away on it own. Good luck . his email address drwilliams098765@gmail.com for advice and for his product

fedalis carol said...

yes Dr Williams herbal medicine is really a permanent cure to tinnitus,just one week of usage,i was completely cured from tinnitus,on thin now i have not experience any thing ringing in my ears.i give all thanks to god,and i pray for him to continue the good work.

karen dish said...

ALL THANKS TO DR WILLIAMS WITH HIS HERBAL PORTION I WAS COMPLETELY CURED FROM A TERRIBLE TINNITUS.
How can I ever stop thanking Dr William for the great deed he have done for me, i got an accident when I was 27 years old, from that day on i started experience ringing ear (tinnitus) i have taken all the western drugs prescribe by various doctor but to no avail . my tinnitus was very loud in the afternoon and I sleep less at night because of this problem i stop my work, few days later i was going through the Internet and I saw a post of so many people testifying about Dr William herbal remedies on how they was being cure for over many years suffering from tinnitus the story Really motivated me that I have to speak with my husband about it, and he said i should give him a try, i contacted Dr William and explain all i have be facing in my life. He assured me that everything is going to be fine if only I can get his herbal portion, i said yes and I requested for it, few days later the herb was sent to me in Kuwait,i started using it as instructed by Dr William for me to take it for 21 Days which I did, can you imagine after talking Dr William herbal medicine for just two weeks i started experience results, it was like a miracle,and now i am permanently cure from this terrible tinnitus, i promise that am going to publish his herb on thing my last breath for the great deed he have done for me. For those with similar ear problem should please contact him on his email address drwilliams098765@gmail his a good man and am proud of him.