A lot of theories seem to float around in the land of Lyme and then become woven into the fabric of the paradigm. DON'T TAKE Q10 IF YOU ARE TREATING BABESIA! Is this right?
First of all, does coenzyme Q10 work? Apparently it does. It is even mentioned in lectures at Harvard as possibly effective for a variety of conditions. It's efficacy in heart failure is pretty well established. It works in the mitochondria of the cell. This is the cell's power house which generates ATP- energy- through the KREBS cycle.
It appears to help cells produce more energy. Patients taking the supplement claim they have increased energy and less fatigue. By the same token, creatine- which I previously discounted- of weight lifter fame, may also improve energy by providing a vehicle for storing ATP.
Atovaquone- Mepron and Malarone also appears to work through a mitochondrial mechanism. It interferes with electron transport- the final stage of the KREBS cycle necessary for cellular energy production. This is considered a possible mechanism of action. It does not involve the coenzyme Q10 pathway. And even if it did, it inhibits an enzymatic conversion in the cell. It's effect would be independent of the amount of Q10 present. And furthermore- there is nothing to suggest that oral Q10 supplements would have any way of getting into bacterial mitochondria.
Q10 and Mepron both have effects in the mitochondria of cells. That is all they have in common. They work on different cellular mechanisms. If Q10 is an effective supplement for Lyme symptoms, then there is no scientific rationale for stopping it when anti-Babesia therapy is prescribed.
I know this contradicts advice I have given patients in the past. But not having the time to research every recommendation, I had taken this on faith. I think it was incorrect advice.